Dr Gianluca Martuscelli, DMD., MMSc

Senior Lecturer in Periodontology

Contact Details

Dr. Gianluca Martuscelli (registration number N. 98) graduated in 1986 from the Dental School at the University of Naples and, in 1988 earned a Certificate in Orthodontics from the same educational institution. Successively in 1995, he received a M.M.Sc. in Oral Biology and, at the same time, a Certificate in Periodontology conferred by Harvard School of Dental Medicine.

From 1986 to 1991 he was Clinical Instructor and Lecturer in Orthodontics, at the University of Naples, Italy; in 1995 he became “Professore a Contratto in Periodontology at the  School of Dental Medicine, University of Chieti, Italy; in 1997 he was appointed Visiting Professor in Periodontology at Harvard School of Dental Medicine Boston, USA; in 1999 Assistant Professor in Periodontology  and Course Director at Tufts School of Dental Medicine, Boston, USA; at the same time, he was Associate Staff, Restorative Service, Department of Dentistry, in the Bone Marrow Transplant Unit at the New England Medical Centre, Boston, USA; currently Dr. Martuscelli is Senior Lecturer in Periodontology and Implantology in the Adult Oral Health Department at Barts & The London, Queen Mary's School of Medicine & Dentistry

Publications:

Publications since 2001

Cornelini R, Covani U, Barone A, Martuscelli G, Piattelli A. Horizontal increase of crestal alveolar bone: reports of two cases. Italian Journal of Osseointegration, 1,  21-31

Corrente G, Abundo R, Cardaropoli D, Cardaropoli G, Martuscelli G.  Long-term evaluation of osseointegrated implants in regenerated and non regenerated bone.  International Journal of Periodontics and Restorative Dentistry, 20(4):390-7

Martuscelli G, Fiorellini JP, Crohin CC, Howell TH.  The effect of interleukin-11 on the progression of ligature-induced periodontal disease in the beagle dog.  Journal of Periodontology, 71(4):573-8

Papas AS, Martuscelli G, Singh ML, Stone C, Bartizek RD, Topmiller KJ, Biesbrock AR, Walters PA.  A study to assess the safety and tolerability of three toothbrushes.  Jouranl of Clinical Dentistry, 13(5):203-6

Papas AS, Clark RE, Martuscelli G, O'Loughlin KT, Johansen E, Miller KB.  A prospective, randomized trial for the prevention of mucositis in patients undergoing hematopoietic stem cell transplantation.  Bone Marrow Transplant (Nature Publishing Group) 31(8):705-12

Cornelini R, Cangini F, Martuscelli G, Wenstrom J. Deprotinized bovine bone and biodegradable membranes to support healing following immediate post-extraction placement of transmucosal dental implants: a short term controlled clinical trial.  International Journal of  Periodontics and  Restorative Dentistry.; 24(6):555-63

Hughes, FJ, Turner W, Belibasakis G; Martuscelli G.  Effects of growth factors and cytokines on osteoblast differentiation. Periodontology 2000,41(25):48-72

Papas AS, He T, Martuscelli G, Singh M, Bartizek RD., Biesbrock AR. The comparative efficacy of stabilized stannous fluoride/sodium hexametaphosphate dentifrice and sodium fluoride/triclosan/copolymer dentifrice for the prevention of periodontitis: a two-year randomized clinical trial. Journal of Periodontology (accepted for publication)

Research interests:

Research efforts are concentrated on clinical trials, in particular different types of dental implants and the management of treatment and failure, periodontal chemotherapeutics and diagnostics, growth factors,  epidemiological study to determine the effect of medications on periodontal disease, treatment of bone marrow transplant therapy-induced mucositis, soft and hard tissue biofilm evaluation in periodontal and healthy patients, bacterial analysis (ceckerboard DNA-DNA hybridization technique) of supra and sub-gingival plaque in patients with Sjögren’s syndrome and lastly, the use of alloplastic materials and biodegradable membranes following immediate post-extraction placement of transmucosal dental implants.

 Another major line of research has involved the development of animal study protocols focused on anti-inflammatory agents (NSAID’s) as modulators of periodontal disease progression, chemotherapeutics and cytokines and their protective role, and proteins used in a specific matrix to promote osteogenesis in critical size defects. For the accomplishment of these studies Dr. Martuscelli has gained valuable experience in the management of both the canine and the rodent study models.
 
Dr. Martuscelli daily clinical activity is focused particularly on surgical procedures aimed to regenerate the lost tissues of the periodontal apparatus using innovative materials and techniques.
Similarly he works with postgraduate students treating partially and fully edentulous patients performing advanced procedures directed to reestablish adequate bone volume in order to facilitate the placement of endosteal dental implants